Research Review: Investigating the Link Between Diabetic Nephropathy and Vision Loss

During the summer of 2024/25, I had the opportunity to undertake a research studentship with the Department of Ophthalmology at the University of Auckland. As I prepare to enter my final year of medical school, I saw this as a valuable chance to deepen my understanding of diabetes and its complications, while gaining hands-on experience in clinical research.

My project focused on diabetic retinopathy—a common complication of type 2 diabetes mellitus (T2DM) and the leading cause of blindness among working-age adults. Specifically, I investigated diabetic macular oedema (DMO), which is the primary cause of vision loss in these patients. Previous studies have suggested a possible link between diabetic nephropathy (DN) and the development of DMO, but the evidence has been inconsistent.

To help clarify this relationship, I conducted a retrospective cross-sectional study examining the connection between DN and DMO in patients with T2DM. The findings of my research indicated that diabetic nephropathy is not a risk factor for DMO status, contributing a new perspective to the ongoing discussion in this area.

One of the most rewarding aspects of this studentship was learning how to carry out a research project from start to finish. I gained insight into the complexities of diabetes-related eye disease and its impact not only on patients but also on their whānau. This experience has strengthened my appreciation for the role of research in improving patient care and has further inspired my journey toward becoming a clinician.

I’m incredibly grateful to the University of Auckland research team—especially Dr Linh Do and Associate Professor Stuti Misra—for their guidance and support throughout the project.